OWA 2013 Initialization Failed to open ev options

Environment: MS EXCH 2013 2 MBX Servers, 2 CAS/HUB, Publiched via TMG. Resource Forest Domain.

EV SRV 10.0.4 R1 CU3 in VM.

We tried to deploy the office mail app in some users, but the EV owa option doesn't work properly, actually the error message appeared such as " Initialization failed"

 

Thanks for any help!

Friendly

GM