Upgrade from 6.0 SP1 to SP2

We are currently on 6.0 SP1 on Windows 2003 standard server sp1. Our version of Exchange is 2003 SP2. We are looking to go to SP2 for Enterprise vault.

Has any one had any issues or heard of anyone having issue's with SP2. Anything I should be aware of. Any info at all would be greatly appreciated. Thanks