I don't recall if it occurred with 20.1 but it's certainly possible. It's really bad with 20.3. Server has 2 CPU sockets, 8 cores for each CPU, 16GB of RAM. Nothing is using the CPU at all when this happens and RAM use is very low. Doesn't seem to be a resource issue.
We have seen some issues with our beremote process using 100% CPU on certain Dell servers (which we have been researching with Dell)
However this does not seem to match your description - as such I encourage you to log formal support cases for a proper investigation