Well Tamir, what more could you ask for, three people all rushing to answer your question! :)
Philip raises a good additional point though, while the edb and stm files are not needed, Backup Exec will automatically exclude them anyway from the backup so your best option is to just select everything and let Backup Exec handle it, as you do need some of the files (which are capable of being backed up) to do a DR restore. And of course you need to ensure you have a backup of your System State data as well, otherwise a DR restore won't work properly.