We are using Backup Exec 12.5 on a MS Server 2008 64-bit with Exchange 2007 and accessing USB 500 Gb backup drives connected to a MS Server 2003 32-bit server that also runs BEX 12.5. The Server 2003 server daily writes successfully to the USB drives, but the Server 2008 server fails. If I mark the device as ON-LINE and try to run any job (backup, inventory, scan, etc.) the USB drive device is immediately flagged as Off-Line. At that point I can go to Windows Explorer and access the drive without problem. The USB drives are shared with Full-Control rights granted. I have tried both B2D devices and Removeable Media with the same results. What can be done to make this work. Thank you in advance for your response.