I'm in the same boat... We recently upgraded from 8.5 to 10.0 and have had nothing but problems. Very simple setup on our end: Windows 2003 Server and Compaq AIT 100 tape drive. No remote agents or anything fancy. We have a nightly job to backup everything on our web server but since going to 10.0, I had to have our networking guys add my server to their nightly backup job because I couldn't make anything work 100% of the time.
We rotate 15 tapes as we backup the server and since going to 10.0, the software has told me that over half of my tapes are bad and unrecognizable. I've tried reformatting, erasing, throwing them against the wall, and nothing helps.
I updated the firmware this morning and it did nothing. I'm using the Veritas driver on my tape drive and based on the last post, it sounds like I might try to go with the HP driver? It couldn't be that simple, could it?
Mike