Hi,
Although your questions are quite you need further investigations for your need.
https://vias.symantec.com/vias/vias/general will be a good start point.
At that side you may enter your parameters and will get good checklist sample.
Your VCS configuration normally will need two nic for heartbeat and two for public network.
Just heartbeats must be in diffrent subnets.
There are some recommendations but they are not always mandatory. You will decide to your configuration.
Version and release information is very important .
For example 5.0 release supports Oracle 9i - 10G R1 and 10G R2.
You must read release notes.
http://seer.entsupport.symantec.com/docs/283886.htm
regards,
ersen