Hello,
when you review NetBackup for Virtual Environments doc (easily googable), there is a note:
"NetBackup for VMware supports backup and recovery of the entire virtual machine for all guest operating systems that are supported by VMware."
As for file-level backups and restores, you must review the same document if your file system is supported.
Please give more descriptive subjects to posts, "NetBackup" is not really very specific in "NetBackup" forum :)
Regards
Michal