Solved! Go to Solution.
I didn't enable Jumbo Frames, although I plan to go talk to my network team in discussing the setup of trunking on the switches with LACP and jumbo frames.
I'm not positive that its a cure-all for everyone, but in each nic on the server itself, there should be options to adjust the buffer size on outgoing/incoming receipts. Ironically though, the solution for one server didn't fix the other server, although the other server is using a similar setup with a deduplication pool instead of a DSSU.
Honestly I feel there is some other process occuring within the software that is causing a delay or not treating an iscsi device as appropriately as it should. When i copied the files using file transfer on windows, it worked extremely fast, but duplication still doesn't work as fast. Could be a windows thing (honestly havent hooked up an iscsi to our linux media servers) but there are a ton of people on the forums who are seeing duplication issues with all sorts of disks, devices, etc.