Check this link. I am sure it will help.
http://customercare.symantec.com/app/answers/detail/a_id/124/~/what-is-the-process-for-opening-a-case-to-resolve-my-issue%3F
One of the main reason for tis popup is that the E-mail scanner has detected some threat. In this scenario I would suggest to download the latest virus definitions then disconnect the machine from the network thereafter restart the machine in SAFE M...
Incorrect permissions cause this problem. To fix the problem, follow the directions in the document :
http://service1.symantec.com/SUPPORT/ent-security.nsf/docid/2002103013521548
If the problem persists, manually uninstall the previously install...
