1 data protection optimization for replication
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Are you planning to use MSDP or a NetBackup Appliance?
Data protection optimization is for deduplication and will also enable replication via AIR.
This license is capacity based - you need 1 license per front-end TB.
If you do not go with capacity based licensing: Platform Base – Complete Edition, you will have to license the DR site as well - similar to Production site. For real DR protection, you will need a Master server at DR with all backups available at DR site.
Host A cannot be a VM - tape is not supported. See Statement of Support for NetBackup 7.x in a Virtual Environment ( Virtualization Technologies ): http://www.symantec.com/docs/TECH127089
If Antivirus Server and Proxy Server are physical machines, they will need Standard Client.
If 'Proxy Server' will be your Backup Host for VMware backups, it will be best to install media server software (Enterprise Server license) to ensure SAN based backups (as oppised to LAN). Why not make this server the Master/Media server with tape attached? Environment seems small enough to have a single master/media server. If tape is in a robotic library, you will need 1 license per library-based tape drive.