Netbackup Application and Database pack

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Ex. 1 esx host
2 x AD
2 x DNS
2 x exchange
2 x sql
1 x file server

exs host requires 1 enterprise client license.  This will cover granular recovery for ALL vm's except AD?
Yes

esx host requires 1 enterprise client license. Each vm requires 1 app/db pack; exception is fileserver needing nothing.
Each vm requires 1 app/db pack;  : False. Not each Guest vm would require app/db pack, instead only 1 app/db pack would be required per tiered ESX host server
exception is fileserver needing nothing.: True
 
It seems the idea of what is needed on the esx host has changed. Can I please get an overview of what is needed on ESX host to what is needed on each VM.
VMware tools is needed on each Guest VM
Except SAP all the application and Database can be licensed under 1 app/db pack per  tiered ESX hosts

 hope this clarifies your doubt.

For further details you can sync up with local  account manager from Symantec. They would  aid you further