BipinV
We're going to need a bit more details about what you have and what you are wanting to do.
You said that you have two 5250 Veritas appliances. What version? How much storage?
Depending on your current licensing model, you may need to purchase additional licenses to allow AIR replication as well as licenses for another master and media. Also need to take into consideration that you'll need an MSDP pool on the remote location for the "offsite" media server.
5250 #1 is running as a master???
5250 #2 is running as a media server??
Going to need more details to help iron this out.