My understanding was that a single master/media server is writing 45 streams simultaneously...
Now, think of the data path (assuming that most master/media servers still only have a single 1Gb NIC).
How many network connections from clients can this 1Gb accommodate, all trying to transfer data at +- 10Mb/sec?
Well, if 45 clients are transferring data at 2Mb/sec each, then 45 streams will not be a problem.
The 1Gb NIC will just about be saturated and can stream a single LTO3 @ 90Mb/sec.
A master server with those specs with 10Gb NIC can handle a lot more incoming data from clients.
It all comes down to network infrastructure and the amount and speed of data transfer from the clients.
As per my previous post - a proper sizing exercise is needed to see where the bottleneck/resource issue is.
It could be a simple matter of insufficient shared memory configured at OS level.
The Planning and Performance Tuning Guides will help you:
Overview of NetBackup performance testing.
http://www.symantec.com/docs/TECH147296
Symantec NetBackup™ 7.0 - 7.1 Backup Planning and Performance Tuning Guide
http://www.symantec.com/docs/DOC4483
Key performance considerations for NetBackup 7.5 master servers http://www.symantec.com/docs/TECH202840
Performance issues observed when running UltraSparc-T series architecture on a NetBackup 7.x Master Server
http://www.symantec.com/docs/TECH204332
Designing your backup system
http://www.symantec.com/docs/HOWTO56078
Improving NetBackup backup performance
http://www.symantec.com/docs/HOWTO44836
NetBackup™ Architecture Overview
https://www-secure.symantec.com/connect/sites/default/files/b-whitepaper_nbu_architecture_overview_12-2008.en-us.pdf
NetBackup 7.6 Best Practices: Optimizing Performance
Updated NetBackup Backup Planning and Performance Tuning Guide for Release 7.5 and Release 7.6
(Not sure if all the HOWTO links are still working - some have been expired and SYMwise seems to be offline at the moment...)