NetBackup client you must be aware of till now. Backup host is defined in your post itself. NBU and VMware came up with joint approch towards V-ray vision hence NBU uses vStorage API to leverage this benefit. This ensures us to protect Guest that too NBU Agent less or with Agent (except if restore is to performed on original host and/or GRT is to be enabled in PASS THROUGH mode)
with 7.5 Abdul had confirm that now OS platform has been extended to cover SLES under backup host pre-reqs. So if you have SLES which is also vCenter you can make it backup host
In case you need to offhost backups from LAN to SAN read below
https://www-secure.symantec.com/connect/blogs/nuts-and-bolts-netbackup-vmware-netbackup-5220-and-sles-based-backup-hosts
for assigning those Data Stores to Backup host, we strictly rely on zoning , we do not want those LUNs to be initialized , or mounted
Below are the steps that we need to follow
Run Following syntax from Backup Host . Run CMD with administrative privileges
· Diskpart automount disabled
o Disabling automount would prevent Windows from automatically mounting any new basic volumes that are added to the system.
· Diskpart automount scrub
o Scrub would Removes volume mount point directories and registry settings for volumes that are no longer in the system. This prevents volumes that were previously in the system from being automatically mounted and given their former volume mount point(s) when they are added back to the system.
Above syntax must be executed prior to zoning is done. Also make note that above service are by default enabled in Windows 2k8 family, and they are restored back to default state after patch is applied. So we need to disabled them manually
· Disable Virtual Disk Service
o After zoning is done and LUNs are visible in Disk management as Basic Online with Healthy status , Disable Virtual Disk Service from Services console. This would prevent this LUNs being visible to others accessing Backup host
Hope above clears your doubts
Also would recommend rather to wait till you get timely revert on assistance from Forum, simulate lab in UAT and evaluate all the options available. Most of your queries get answered there itself . More over it would be practise for your self too ;-)