Hi,
You need to configure remote agent utility which is on your RHEL box since the oracle database is on this box.
Configuring the oracle agent is just adding your exisiting oracle instance (which you want to backup) to remote agent utility and in turn letting both remote agent utility and backup exec server to communicate with each other and take backups. Just adding the instance will not have any impacts on the database.
However when you take backups there might be impacts based on the backup type. For e.g. if your Oracle database is in Archieve Log Mode then backup exec can take 'online' database backups and your applications using the database wont see much impacts, on the other hand if your Oracle database is in NoArchivelog mode then backup exec has take Oracle database 'offline' before it could take backups, this will deffinitely impact your applications which use this database. Irespective of database being in Archive log mode or NoArchive log mode you can still take offline backups. All these options can be found in Backup Exec UI. Backup Exec uses RMAN to take oracle backups.
Hope this helps!