We're having a strange one. The server (WK6, for what it's worth) is backing up a bunch of other machines that have Remote Agents installed. One machine in particular, WK22, fails almost every night unless its Remote Agent service is restarted beforehand. The network connection & drivers have been updated & tested, we've defrag'd and checked and patched and tweaked the machine (yes, we read the KnowledgeBase), but still we get the failures. It's always on WK22, and it's not always at the same point in the data. The Remote Agents are on the latest versions all the way 'round.
What do you think, folks?