I have been using 4GB files for backups with no append but have been considering going to 40GB files and using append. Do you have any advice about this? Is a 40GB file too large for B2D?
I'd stay with 4 GB Overwrite. Also, if you Append, ALL of the BKF files are considered part of one big multi-volume set, and all are governed by the same OPP. That is if you have a two week OPP, and append, even BKF files created two months ago are protected for two weeks following last night's backup.
Don't see any real reason to have multiple B2D folders, and if you knock it back to one, then setting Max Concurrent to 4 ought to do what you want.
As for the policies, couldn't you setup a policy for the Duplicate Job that would release the next backup when it (the duplicate job) finishes?