Paul,
Backup Exec System Recovery (BESR) is often used in conjunction with Backup Exec, and some people decide to use one or the other. BESR is the gold standard in DR solutions.
BESR does indeed give you the ability to restore to dissimilar hardware. For instance, if you have a Dell server on its last leg, and you have an HP server on standby ready to go once the server fails, you can simple lay the image from the Dell onto the HP using the BESR RestoreAnywhere option, and the HP will boot up just as the Dell did (with new drivers, of course). This is similar to how how sysprep works.
You would setup BESR to backup to USB, network drive, SAN, NAS, DAS, etc.
In the event of a crash, you would boot from the CD (or other boot method previously set up) into the Symantec Recovery Environment. From there, you can access the recovery points and restore them.
Check this out:
http://www.symantec.com/business/playerdetail.jsp?cid=besr_dissimilar_11m&sg=business&type=videos&lg...