To optimize throughput, you want the largest blocksize that you can specify, make the buffer at least twice the blocksize and number of buffers at least 5
For machines supporting a max of 64K block size, I use
BlkSize 64K Buffer 128K Number of Buffers 10
Just be sure that you have plenty of RAM on the media server. Also, as long as the buffers are never depleted, a larger total buffer will not speed things up at all, and will hold RAM back from the OS while a backup is running.