For everyone expecting Backup Exec or any other Backup product to work and work with 100% of your throughput, you are seriously mistaken.
Backup apps by nature will find every weak link in your network, from disk I/O, file system inefficienies, LAN throughput, poor drivers(both LAN, SCSI, and tape), etc...
Backup tuning is no different than a hardcore gamer that tweaks every little setting in a video card to get the most frames per second (FPS)
That said, look at disk tuning both disk alignment, and automated defrag tools, look at NIC trunking, B2D, block size changes to tape, and more... There is no right answer, and becuase of the wide types of data, there is no silver bullet to this problem. You can only test, change settings, and test again...