v12.5 offers an agent for Virtual Servers that will backup a live VS environment
from
http://www.symantec.com/business/products/family.jsp?familyid=backupexec
Backup Exec Agent for VMware Virtual Infrastructures The new Backup Exec 12.5 Agent for VMware Virtual Infrastructures delivers complete disk-to-disk-to-tape based data protection for growing VMware virtual environments while protecting existing physical server environments through one flexible console. Backup Exec 12.5 can quickly restore individual files and folders from a single image-level backup - eliminating the time and storage requirements of a second file level backup
One agent delivers comprehensive data protection to an unlimited number of VMware virtual guest systems
Comprehensive backup application for virtual systems and physical systems supporting disk and tape storage environments
Integration with VMware Consolidate Backup (VCB) to maximize backup and recovery performance
Granular data recovery for VMware Infrastructures saves time and lowers cost