I'm in the same boat with a vxa2 tape drive. The soft errors started after the tape drive was replaced by IBM in an attempt to solve a BE renaming of tapes issues. I still get the renaming problem, but not quite as bad, but the soft error numbers are crazy. hundreds of soft write errors and tens of thousands of soft read errors per back up.
Working with IBM has ran me around in circles and accomplished nothing but using all my weekends up. Working with support at Symantec hasn't gotten me much further either.
The one thing I see as the issue, is the change in firmware of the tape drive. The tools do not allow you to switch back and IBM can't get me an older firmware version to test. They also seem to refuse to work with the BE support people on this. Constantly want me to repeat the same steps that failed to solve the issue the last 4 times. Also they seem to think I should run the native NT backup as a test. NT backup does not report soft errors! you just one day find out nothing is working with no idea why.
Exabyte has a newer firmware version out for the vxa2 tape drive, but neglected to create a new vxatool that allows a person to use it.