NFS mounts are supported in VCS 4.1 and 5.0. On Solaris you are offered 3 options for mount: VxFS, ufs and nfs. iSCSI is supported by the OS, not by VCS. You need to have iSCSI drivers on the OS that see the LUNs and in turn put them into /dev/dsk. I use iSCSI for mobile classes because we cannot run FC on Tadpole (SPARC) laptops. Volume Manager sees the devices just like any other.
I suppose you could configure some sort of dual path approach with iSCSI. Since VM sees them as disks, as long as it can see two devices as being identical, it should be able to handle DMP. VCS doesn't care about storage, it simply uses what VM hands it.