You can see these kind of high numbers on single tapes if your data on particular tape contains lot of big DB files. The way DBAs define data files in database, they assign file name and size of the file to be used. If file size is say 2 GB, you will see 2GB used at Filesystem level but within database you may be using only 10% of 2GB. When NetBackup backup these kind of files it get high compression rate because it's compressing the empty space within the file.
BTW, I have lots of LTO-3 tapes with more than 2 TB on one tape. :)