Dude, apologies if I came across a bit harsh, and I accept that I did. Sorry.
Look, when you raise a question we all need:
1) O/S version and patch level of all machines involved.
2) NetBackup and patch level of all machines involved.
3) A brief synopsis of the architecture of your environment, i.e. what it connected to what and how...
4) Error status number, and hopefully extracts from failed jobs or log files.
5) A description of all the different things that you have tried so far to resolve the issue.
6) If it was working before and has now stopped, what exactly were *all* the changes made.
HTH, Regards, D.
P.S. Not sure if you know, but this command usually gives great starting points to resolve any error numbers...
$ bperror -S <num> -r
e.g.
$ bperror -S 41 -r
...will list all the recommended actions that a user should follow for a status 41 error before contacting official support.
BTW, this is a user based forum that is kindly hosted by Symantec. Very few, if any, actual Symantec employees ever look in here. For the official Symantec Support you need a support contract.