Atif,
Check with your tape library vendor on the connectivity of the tape device & robotic path (e.g. SCSI/FC router, compatibility matrix, etc)
For Netbackup end, you need to purchase SAN Media Server license for the hosts and if you're (or want to) sharing tape drives between these hosts and the backup server, SSO is needed. But first, you must get your backup server and tape library connected to SAN.
Another approach is to perform snapshot, or shadowImage, etc on the SAN storage and mount to netbackup server to perform backup. In this appraoch you only have to connect the backup server to SAN (for mounting of snapshots) without purchasing other NBU options and connectivity for tape library to SAN. The drawback is to have extra disk space for snapshot(s).